Nutrient Core will help you understand the fundamental genetic interactions with diet and lifestyle and indicate whether specific functions require further genetic testing. It includes genes that have been shown to affect:
- food response – gluten (coeliac) and lactose intolerance
- caffeine – sensitivity and metabolism
- gut microbiome – diversity
- vitamin need – vitamins A, B9 (folate), B12 (cobalamin), C, D and K
- blood pressure – sodium-potassium balance & salt sensitive hypertension
- detoxification – glutathione
- metabolism – blood sugar control (insulin), appetite (leptin)
- inflammation – specific (infection response) and systemic
- circadian rhythm – early bird or night owl predisposition
This genetic test can be used to analyse how your gene variants can affect food tolerance (and intolerance), appetite control and blood sugar balance, vitamin and mineral needs, detoxification ability, and susceptibility to inflammation and infection.
The Metabolics Report gives us new insights into how our genes affect our unique metabolism, which plays a crucial role in regulating energy, promoting longevity, and maintaining good health.
Metabolism refers to all the chemical reactions happening in our cells, like building up and breaking down substances. This includes making things like sugars, fats, proteins, and DNA (anabolism) and breaking them down to release energy (catabolism). The balance between these processes is essential for our energy levels and the overall health of our cells.
The report looks at more than 40 genes and 50 genetic variations (SNPs) that have a strong impact on six important pathways related to metabolism. These pathways include controlling appetite, sensing nutrients, managing sugar and fat, regulating cholesterol and bile, overseeing mitochondria (the cell’s energy powerhouse), and handling inflammation.
Detoxification is the physiological removal of toxic substances from the human body. It is mainly carried out by the liver, and to a lesser extent the small intestine, kidneys and lungs. Substances such as nutrients, food additives, pesticides, medications, air pollutants, alcohol and hormones are transformed from being fat-soluble to water-soluble, allowing them to be more easily excreted from the body. The process occurs in two major phases: Phase I primes toxic molecules for deactivation and Phase II finishes the deactivation and prepares for elimination.
Poor detoxification can cause symptoms such as headaches, muscle aches, fatigue, allergies, skin disorders, weight gain, bloating, acid reflux and heartburn, excessive sweating, chronic infections, subfertility, low libido, poor mental function and low stress tolerance.
The Detoxification test looks at specific genes related to how well your liver processes these toxins. It checks genes involved in different phases of detoxification, helping to identify any areas that might need extra support. The report then suggests personalized nutritional steps to help your body detoxify better.
Histamine is a chemical messenger in our body that does different jobs like sending messages in our brain, helping our stomach digest food, and being part of our immune system’s response to stress, injury, or allergies.
When we have histamine intolerance, it means our body can’t handle the amount of histamine it has. This can happen when our body doesn’t break down histamine fast enough, making it build up and cause problems. Symptoms can include things like skin irritation, trouble breathing, digestive issues, headaches, trouble sleeping, and feeling anxious.
The Histamine Intolerance test looks at our genes and nutrients to see if there are any issues in breaking down and getting rid of histamine. Sometimes, certain factors like gastrointestinal problems or certain foods and medications can make it harder for our body to break down histamine. If there’s not enough of a certain enzyme called diamine oxidase (DAO) in our gut or another enzyme called histamine-n-methyl-transferase (HNMT) in our nervous system and lungs, it can lead to too much histamine in our body.
Methylation is a process where small groups of atoms are added to other molecules in our body. This process is super important and happens a lot in our cells, helping with tons of essential functions.
When methylation isn’t balanced – either too little or too much – it can make us more likely to have chronic health issues like heart disease, fatigue, infertility, immune problems, and mood disorders. It can even increase the risk of cancer and premature aging.
The Methylation genetic test looks at genes involved in five different cycles in our body. These cycles help with things like processing certain vitamins and minerals (like B6, B9, and B12), as well as dealing with chemicals, hormones, and heavy metals. The test results can show if someone might struggle with processing these things efficiently and give advice on how to support their body better.
Oestrogen is one of the two major female steroidal sex hormones, the other being progesterone. Men also require oestrogen for producing sperm and maintaining libido, but at significantly lower levels. Oestrogen main role is to increase the growth and production of cells. It is responsible for the development of the female reproductive system and is also involved in maintaining bone density, blood clotting and affects hair, skin, mucous membranes and pelvic muscles.
When oestrogen levels aren’t balanced, it can cause issues like heavy periods, skin-related issues including acne and rashes, and some types of breast cancer in women.
The Oestrogen Balance test looks at how certain genes affect estrogen levels in the body, as well as factors like diet and environment. It’s helpful for women who think their health issues might be related to oestrogen levels.
Steroid hormones are a type of hormone made from cholesterol. They include hormones like progesterone, estrogen, testosterone, DHEA, and cortisol. These hormones help control many important functions in the body, like reproduction, metabolism, inflammation, and the immune system. They travel in the blood attached to specific proteins and are broken down in the liver and other tissues.
When steroid hormones are out of balance, it can cause various symptoms in both men and women. These symptoms include trouble getting pregnant, low sex drive, acne, excessive facial hair in women, mood swings, poor memory, weight gain, and hormone-related cancers like breast or prostate cancer.
The Hormones test looks at genes related to these hormones and how variations in these genes can affect hormone balance. It also examines how nutrients and the environment can influence hormone balance. This test is recommended for people experiencing symptoms of hormone imbalance like the ones mentioned above.
The thyroid is an endocrine gland in the neck that produces two thyroid hormones – triiodothyronine (T3) and thyroxine (T4), and calcitonin – important for your body’s metabolism, growth, and heart health. It can be influenced by your genes and environmental factors such as what you eat, stress, and exposure to certain substances.
When the thyroid isn’t working properly, it can lead to various issues like problems with your metabolism, immune system, and even cancer. Having too little or too much of these hormones can cause different symptoms. For example, if you don’t have enough, you might feel tired, gain weight, or feel depressed. If you have too much, you might feel anxious, have trouble sleeping, or lose weight.
The Thyroid Balance report looks at your genes related to how these hormones are made, how they’re transported and used in your body, and factors that can affect them like stress or inflammation. It helps understand how your body handles thyroid hormones and if there are any risks for problems like autoimmune diseases.